Effective results for Helicobacter canadensis MIT 98-5491 (eggnog40)
Summary
Number of putative secreted proteins: 362
- Predicted by T4SEpre: 0
- Predicted by EffectiveELD: 149 eukaryotic-like domains, contained in 362 proteins (42 high, 320 medium Z-score)
Predicted protein secretion systems (parentheses indicate weak positive predictions lacking more than 50% of core proteins of a secretion system): Type VI
Protein based results
Putative secreted proteins (weak evidence indicated by parentheses)
Protein | EffectiveT3 | EffectiveCCBD | T4SEpre | EffectiveELD | Predotar |
---|---|---|---|---|---|
537970.HCMG_00927 | (PF04561) (PF04983) (PF04565) (PF10385) (PF04998) (PF04997) (PF00623) (PF00562) (PF04563) (PF05000) (PF04560) | (mitochondrial) | |||
537970.HCAN_0216 | (PF04561) (PF04983) (PF04565) (PF10385) (PF04998) (PF04997) (PF00623) (PF00562) (PF04563) (PF05000) (PF04560) | (mitochondrial) | |||
537970.HCMG_00251 | (PF03947) (PF00181) | mitochondrial | |||
537970.HCAN_0575 | (PF03947) (PF00181) | mitochondrial | |||
537970.HCAN_0588 | PF00861 | (mitochondrial) | |||
537970.HCMG_00608 | PF02516 | ER | |||
537970.HCMG_00267 | (PF00344) | ER | |||
537970.HCMG_00264 | PF00861 | (mitochondrial) | |||
537970.HCMG_00861 | (PF14743) | ER | |||
537970.HCAN_1176 | (PF14743) | ER | |||
537970.HCAN_1081 | (PF03054) | ER | |||
537970.HCAN_0116 | (PF00551) | (mitochondrial); mitochondrial | |||
537970.HCMG_00255 | PF00252 | (mitochondrial) | |||
537970.HCMG_00254 | PF00189 (PF07650) | (mitochondrial) | |||
537970.HCMG_00253 | (PF00237) | mitochondrial | |||
537970.HCMG_00252 | (PF00203) | (mitochondrial) | |||
537970.HCMG_01035 | (PF00551) | (mitochondrial); mitochondrial | |||
537970.HCMG_00930 | PF00687 | mitochondrial; (mitochondrial) | |||
537970.HCAN_0486 | (PF10431) | (mitochondrial) | |||
537970.HCAN_0868 | (PF00430) | ER | |||
537970.HCAN_0869 | (PF00430) | ER | |||
537970.HCAN_0864 | (PF00551) | (ER) | |||
537970.HCAN_0729 | PF02516 | ER | |||
537970.HCAN_0277 | (PF06965) | ER | |||
537970.HCAN_0205 | (PF00013) | ER; (ER) | |||
537970.HCAN_0665 | (PF00551) | (mitochondrial) | |||
537970.HCAN_0514 | (PF00453) | mitochondrial; (mitochondrial) | |||
537970.HCAN_0515 | (PF01632) | (mitochondrial) | |||
537970.HCMG_00217 | (PF00398) | (ER) | |||
537970.HCMG_01616 | (PF06965) | ER | |||
537970.HCAN_0213 | PF00687 | mitochondrial; (mitochondrial) | |||
537970.HCAN_0930 | PF02516 | ER | |||
537970.HCMG_00761 | (PF03054) | ER | |||
537970.HCMG_00160 | (PF10431) | (mitochondrial) | |||
537970.HCMG_01317 | (PF02348) | mitochondrial | |||
537970.HCMG_00952 | (PF00551) | (mitochondrial) | |||
537970.HCAN_0084 | (PF03840) | ER | |||
537970.HCAN_0421 | (PF13664) | ER | |||
537970.HCMG_00547 | (PF00430) | ER | |||
537970.HCMG_00546 | (PF00430) | ER | |||
537970.HCMG_00091 | (PF13664) | ER | |||
537970.HCMG_00324 | (PF06325) | (mitochondrial) | |||
537970.HCAN_1461 | (PF08840) | ER | |||
537970.HCMG_01067 | (PF03840) | ER | |||
537970.HCAN_1287 | (PF02348) | mitochondrial | |||
537970.HCAN_0576 | (PF00203) | (mitochondrial) | |||
537970.HCAN_0577 | (PF00237) | mitochondrial | |||
537970.HCAN_0578 | PF00189 (PF07650) | (mitochondrial) | |||
537970.HCAN_0579 | PF00252 | (mitochondrial) | |||
537970.HCMG_00189 | (PF01632) | (mitochondrial) | |||
537970.HCMG_00188 | (PF00453) | mitochondrial; (mitochondrial) | |||
537970.HCMG_00342 | (PF00551) | (mitochondrial) | |||
537970.HCAN_0591 | (PF00344) | ER | |||
537970.HCAN_0596 | PF00411 | (mitochondrial) | |||
537970.HCAN_0597 | (PF00163) | (mitochondrial) | |||
537970.HCMG_00271 | PF00411 | (mitochondrial) | |||
537970.HCMG_00272 | (PF00163) | (mitochondrial) | |||
537970.HCMG_01471 | (PF00886) | mitochondrial | |||
537970.HCAN_1438 | (PF00886) | mitochondrial | |||
537970.HCMG_01496 | (PF08840) | ER | |||
537970.HCAN_0647 | (PF06325) | (mitochondrial) | |||
537970.HCAN_0610 | (PF02527) | (plastid) | |||
537970.HCAN_0617 | (PF03484) (PF03147) | ||||
537970.HCAN_0616 | (PF01409) (PF02912) | ||||
537970.HCAN_0905 | (PF05496) (PF05491) | ||||
537970.HCAN_0589 | PF03719 PF00333 | ||||
537970.HCAN_0584 | PF00673 PF00281 | ||||
537970.HCMG_00285 | (PF02527) | (plastid) | |||
537970.HCMG_00260 | PF00673 PF00281 | ||||
537970.HCMG_00265 | PF03719 PF00333 | ||||
537970.HCMG_00461 | (PF03948) (PF01281) | ||||
537970.HCAN_1173 | (PF02769) (PF00586) | ||||
537970.HCAN_0750 | (PF00013) (PF03726) | ||||
537970.HCMG_00933 | (PF00584) | (mitochondrial); not used | |||
537970.HCMG_00931 | (PF00298) (PF03946) | ||||
537970.HCMG_00748 | (PF02769) (PF00586) | ||||
537970.HCAN_0783 | (PF03948) (PF01281) | ||||
537970.HCAN_0657 | (PF00733) (PF13537) | ||||
537970.HCAN_0654 | (PF00733) (PF13537) | ||||
537970.HCAN_1334 | (PF02769) (PF00586) | ||||
537970.HCAN_0643 | (PF00551) | (mitochondrial) | |||
537970.HCAN_0204 | (PF01041) | (mitochondrial) | |||
537970.HCAN_0662 | (PF00733) (PF13537) | ||||
537970.HCMG_00583 | (PF05496) (PF05491) | ||||
537970.HCMG_01349 | (PF02769) (PF00586) | ||||
537970.HCAN_0477 | (PF04305) | (ER) | |||
537970.HCMG_00339 | (PF00733) (PF13537) | ||||
537970.HCAN_0212 | (PF00298) (PF03946) | ||||
537970.HCAN_0210 | (PF00584) | (mitochondrial); not used | |||
537970.HCAN_1317 | (PF02769) (PF00586) | ||||
537970.HCMG_00940 | (PF01041) | (mitochondrial) | |||
537970.HCMG_00319 | (PF00551) | (mitochondrial) | |||
537970.HCMG_00408 | (PF00733) (PF13537) | ||||
537970.HCMG_00797 | (PF06071) | (plastid) | |||
537970.HCAN_1067 | (PF02769) (PF00586) | ||||
537970.HCAN_1114 | (PF06071) | (plastid) | |||
537970.HCAN_0730 | (PF00733) (PF13537) | ||||
537970.HCMG_00334 | (PF00733) (PF13537) | ||||
537970.HCMG_00331 | (PF00733) (PF13537) | ||||
537970.HCMG_00428 | (PF00013) (PF03726) | ||||
537970.HCAN_0158 | (PF03102) | (mitochondrial) | |||
537970.HCMG_00987 | (PF03102) | (mitochondrial) | |||
537970.HCMG_00985 | (PF02348) | (mitochondrial) | |||
537970.HCMG_00858 | (PF02769) (PF00586) | ||||
537970.HCAN_0598 | (PF01000) (PF01193) | ||||
537970.HCAN_0599 | (PF01196) | (mitochondrial) | |||
537970.HCAN_0595 | PF00416 | (mitochondrial) | |||
537970.HCMG_00292 | (PF03484) (PF03147) | ||||
537970.HCMG_00291 | (PF01409) (PF02912) | ||||
537970.HCMG_00270 | PF00416 | (mitochondrial) | |||
537970.HCMG_00273 | (PF01000) (PF01193) | ||||
537970.HCMG_00274 | (PF01196) | (mitochondrial) | |||
537970.HCMG_01470 | (PF00448) (PF02978) | ||||
537970.HCAN_1437 | (PF00448) (PF02978) | ||||
537970.HCAN_0160 | (PF02348) | (mitochondrial) | |||
537970.HCAN_0761 | (PF13393) | ||||
537970.HCAN_0298 | (PF13541) | ||||
537970.HCAN_0907 | (PF02938) | ||||
537970.HCAN_0583 | (PF17136) | ||||
537970.HCAN_0582 | PF00238 | ||||
537970.HCAN_0581 | PF00366 | ||||
537970.HCAN_0580 | (PF00831) | ||||
537970.HCAN_0587 | PF00347 | ||||
537970.HCAN_0586 | PF00410 | ||||
537970.HCAN_0831 | (PF01668) | ||||
537970.HCMG_00262 | PF00410 | ||||
537970.HCMG_00263 | PF00347 | ||||
537970.HCMG_00266 | PF00828 | ||||
537970.HCMG_00464 | (PF07650) | ||||
537970.HCMG_00463 | (PF10431) | ||||
537970.HCMG_00468 | (PF01171) | ||||
537970.HCMG_01245 | (PF08459) | ||||
537970.HCMG_01021 | (PF13507) | ||||
537970.HCAN_1554 | (PF02677) | ||||
537970.HCAN_1429 | (PF10431) | ||||
537970.HCMG_00869 | (PF02130) | ||||
537970.HCMG_00863 | (PF04305) | ||||
537970.HCMG_00864 | (PF06965) | not used | |||
537970.HCMG_00865 | (PF03102) | ||||
537970.HCMG_00439 | (PF13393) | ||||
537970.HCAN_1391 | (PF13537) | ||||
537970.HCAN_1178 | (PF04305) | ||||
537970.HCAN_1085 | (PF14622) | ||||
537970.HCAN_0843 | (PF13177) | ||||
537970.HCAN_0338 | (PF02348) | ||||
537970.HCAN_0337 | (PF01041) | ||||
537970.HCAN_0029 | (PF01250) | ||||
537970.HCAN_0242 | (PF10431) | ||||
537970.HCMG_00257 | PF00366 | ||||
537970.HCMG_00256 | (PF00831) | ||||
537970.HCMG_00250 | PF00276 | ||||
537970.HCMG_01386 | (PF13541) | ||||
537970.HCMG_01387 | (PF00448) | ||||
537970.HCMG_00259 | (PF17136) | ||||
537970.HCMG_01257 | (PF05066) | ||||
537970.HCMG_00388 | (PF10576) | ||||
537970.HCMG_00816 | (PF00398) | ||||
537970.HCMG_00925 | (PF00164) | ||||
537970.HCMG_00924 | PF00177 | ||||
537970.HCMG_00929 | (PF00466) | ||||
537970.HCMG_00928 | (PF16320) | ||||
537970.HCAN_1348 | (PF00448) | ||||
537970.HCAN_1349 | (PF10609) | ||||
537970.HCAN_1354 | (PF13541) | ||||
537970.HCAN_0101 | (PF01501) | ||||
537970.HCAN_0322 | (PF04127) | ||||
537970.HCAN_0035 | (PF05496) | ||||
537970.HCAN_0259 | (PF01041) | ||||
537970.HCMG_00664 | (PF10576) | ||||
537970.HCMG_00248 | PF00297 | ||||
537970.HCMG_00249 | (PF00573) | ||||
537970.HCMG_00247 | PF00338 | ||||
537970.HCMG_01624 | (PF00709) | ||||
537970.HCMG_00807 | (PF02410) | ||||
537970.HCMG_00935 | (PF03143) | ||||
537970.HCMG_00939 | (PF00013) | ||||
537970.HCAN_1355 | (PF00448) | ||||
537970.HCAN_0790 | (PF01171) | ||||
537970.HCAN_0264 | (PF00162) | ||||
537970.HCAN_0860 | (PF00829) | ||||
537970.HCAN_0861 | (PF01016) | ||||
537970.HCAN_0862 | (PF01018) | ||||
537970.HCMG_00659 | (PF14602) | ||||
537970.HCMG_00721 | (PF01687) | ||||
537970.HCMG_01528 | (PF01106) | ||||
537970.HCMG_00345 | (PF01041) | ||||
537970.HCMG_01521 | (PF02576) | ||||
537970.HCAN_1219 | (PF08459) | ||||
537970.HCAN_1506 | (PF01041) | ||||
537970.HCAN_1507 | (PF14602) | ||||
537970.HCMG_00900 | (PF10431) | ||||
537970.HCAN_1329 | (PF03143) | ||||
537970.HCAN_1325 | (PF03462) | ||||
537970.HCMG_00210 | (PF01649) | ||||
537970.HCMG_01619 | (PF00709) | ||||
537970.HCMG_00743 | (PF01195) | ||||
537970.HCMG_00123 | (PF02873) | ||||
537970.HCAN_0127 | (PF13507) | ||||
537970.HCAN_0498 | (PF13184) | ||||
537970.HCAN_0092 | (PF06325) | ||||
537970.HCAN_0013 | (PF00709) | ||||
537970.HCAN_0012 | (PF13393) | ||||
537970.HCAN_0785 | (PF10431) | ||||
537970.HCAN_0786 | (PF07650) | ||||
537970.HCAN_0270 | (PF02130) | ||||
537970.HCAN_0276 | (PF03102) | ||||
537970.HCMG_00004 | (PF01041) | ||||
537970.HCMG_00005 | (PF02348) | ||||
537970.HCMG_01357 | (PF03462) | ||||
537970.HCMG_01519 | (PF11987) | ||||
537970.HCMG_01192 | (PF01171) | ||||
537970.HCAN_1201 | (PF06414) | ||||
537970.HCAN_1518 | (PF01171) | ||||
537970.HCAN_1022 | (PF00551) | ||||
537970.HCAN_1020 | (PF06421) | ||||
537970.HCAN_0642 | (PF01041) | ||||
537970.HCAN_0209 | (PF03143) | ||||
537970.HCAN_0200 | (PF00551) | ||||
537970.HCAN_0201 | (PF14602) | ||||
537970.HCAN_0668 | (PF01041) | ||||
537970.HCAN_0666 | (PF14602) | ||||
537970.HCAN_0688 | (PF01937) | ||||
537970.HCMG_00030 | (PF01121) | ||||
537970.HCMG_00585 | (PF02938) | ||||
537970.HCMG_00211 | (PF03462) | ||||
537970.HCMG_00366 | (PF01937) | ||||
537970.HCMG_01509 | (PF03054) | ||||
537970.HCMG_00699 | (PF06421) | ||||
537970.HCMG_00880 | (PF01041) | ||||
537970.HCAN_0473 | (PF00889) | ||||
537970.HCAN_0474 | (PF00318) | ||||
537970.HCAN_0218 | PF00177 | ||||
537970.HCAN_0217 | (PF00164) | ||||
537970.HCAN_0215 | (PF16320) | ||||
537970.HCAN_0214 | (PF00466) | ||||
537970.HCMG_00023 | (PF01192) | ||||
537970.HCMG_00594 | (PF06418) | ||||
537970.HCMG_00593 | (PF00551) | ||||
537970.HCMG_00200 | (PF14714) | ||||
537970.HCMG_00750 | (PF01501) | ||||
537970.HCMG_00343 | (PF14602) | ||||
537970.HCMG_01520 | (PF02033) | ||||
537970.HCMG_01159 | (PF02677) | ||||
537970.HCMG_00972 | (PF14602) | ||||
537970.HCAN_1229 | (PF00958) | ||||
537970.HCAN_1228 | (PF05066) | ||||
537970.HCAN_0195 | (PF01501) | ||||
537970.HCAN_0192 | (PF00551) | ||||
537970.HCAN_0534 | (PF01649) | ||||
537970.HCAN_0535 | (PF03462) | ||||
537970.HCMG_00560 | (PF01142) | ||||
537970.HCMG_00765 | (PF14622) | ||||
537970.HCMG_01561 | (PF05697) | ||||
537970.HCMG_01361 | (PF03143) | ||||
537970.HCMG_01364 | (PF02769) | ||||
537970.HCMG_00943 | (PF14602) | ||||
537970.HCMG_00944 | (PF00551) | ||||
537970.HCMG_00418 | (PF12344) | ||||
537970.HCMG_00949 | (PF01501) | ||||
537970.HCMG_01143 | (PF13393) | ||||
537970.HCMG_01416 | (PF01795) | ||||
537970.HCAN_1491 | (PF01106) | ||||
537970.HCAN_0186 | PF00312 | ||||
537970.HCMG_00701 | (PF00551) | ||||
537970.HCMG_00258 | PF00238 | ||||
537970.HCAN_0452 | (PF02873) | ||||
537970.HCAN_0526 | (PF14714) | ||||
537970.HCAN_0986 | (PF10576) | ||||
537970.HCAN_0980 | (PF14602) | ||||
537970.HCMG_01258 | (PF00958) | ||||
537970.HCMG_00172 | (PF13184) | ||||
537970.HCMG_00318 | (PF01041) | ||||
537970.HCMG_01557 | (PF13541) | ||||
537970.HCMG_01315 | (PF01106) | ||||
537970.HCMG_00407 | PF02516 | ||||
537970.HCMG_00405 | PF00572 | ||||
537970.HCMG_00958 | PF00312 | ||||
537970.HCMG_01421 | (PF10431) | ||||
537970.HCAN_1485 | (PF02576) | ||||
537970.HCAN_1484 | (PF02033) | ||||
537970.HCAN_1483 | (PF11987) | ||||
537970.HCMG_01425 | (PF13537) | ||||
537970.HCAN_1069 | (PF01501) | ||||
537970.HCAN_1062 | (PF01195) | ||||
537970.HCAN_0083 | (PF01765) | ||||
537970.HCAN_0427 | (PF03652) | ||||
537970.HCAN_0882 | (PF01142) | ||||
537970.HCMG_00098 | (PF03652) | ||||
537970.HCMG_00542 | (PF00551) | ||||
537970.HCMG_00540 | (PF01018) | ||||
537970.HCMG_00148 | (PF00318) | ||||
537970.HCMG_00147 | (PF00889) | ||||
537970.HCMG_01230 | (PF06414) | ||||
537970.HCMG_01307 | (PF02403) | ||||
537970.HCMG_01126 | (PF01250) | ||||
537970.HCMG_01120 | (PF05496) | ||||
537970.HCAN_1474 | (PF03054) | ||||
537970.HCMG_01050 | (PF01501) | ||||
537970.HCMG_01059 | (PF06325) | ||||
537970.HCAN_1278 | (PF02403) | ||||
537970.HCAN_1290 | (PF14602) | ||||
537970.HCMG_01379 | (PF00448) | ||||
537970.HCAN_1124 | (PF02410) | ||||
537970.HCAN_0516 | (PF00707) | ||||
537970.HCAN_0728 | PF00572 | ||||
537970.HCAN_0438 | (PF01715) | ||||
537970.HCAN_0540 | (PF00398) | ||||
537970.HCAN_0944 | (PF06965) | ||||
537970.HCAN_0949 | (PF13603) | ||||
537970.HCMG_00151 | (PF04305) | ||||
537970.HCMG_01206 | (PF01041) | ||||
537970.HCMG_00424 | (PF02843) | ||||
537970.HCMG_01068 | (PF01765) | ||||
537970.HCAN_1285 | (PF01106) | ||||
537970.HCAN_1041 | (PF01687) | ||||
537970.HCAN_0302 | (PF05697) | ||||
537970.HCAN_1132 | (PF00398) | ||||
537970.HCAN_0711 | (PF10576) | ||||
537970.HCMG_00521 | (PF13177) | ||||
537970.HCAN_0572 | PF00297 | ||||
537970.HCAN_0573 | (PF00573) | ||||
537970.HCAN_0571 | PF00338 | ||||
537970.HCAN_0574 | PF00276 | ||||
537970.HCMG_01320 | (PF14602) | ||||
537970.HCMG_00982 | (PF01041) | ||||
537970.HCMG_01584 | (PF04127) | ||||
537970.HCAN_0388 | (PF13177) | ||||
537970.HCAN_0387 | (PF02367) | ||||
537970.HCAN_0362 | (PF01121) | ||||
537970.HCMG_00538 | (PF00829) | ||||
537970.HCMG_00539 | (PF01016) | ||||
537970.HCMG_00628 | (PF13603) | ||||
537970.HCAN_0746 | (PF02843) | ||||
537970.HCMG_00190 | (PF00707) | ||||
537970.HCMG_00623 | (PF06965) | ||||
537970.HCAN_0740 | (PF12344) | ||||
537970.HCMG_01462 | (PF10431) | ||||
537970.HCAN_1441 | (PF01746) | ||||
537970.HCAN_1440 | (PF01782) | ||||
537970.HCAN_1442 | (PF01245) | ||||
537970.HCMG_00842 | (PF00586) | ||||
537970.HCMG_00841 | (PF10609) | ||||
537970.HCAN_1158 | (PF00586) | ||||
537970.HCAN_1157 | (PF10609) | ||||
537970.HCAN_0172 | (PF14602) | ||||
537970.HCAN_0355 | (PF01192) | ||||
537970.HCAN_0915 | (PF00551) | ||||
537970.HCAN_0916 | (PF06418) | ||||
537970.HCMG_00509 | (PF01668) | ||||
537970.HCMG_00055 | (PF02367) | ||||
537970.HCMG_00506 | (PF01509) | ||||
537970.HCMG_00056 | (PF13177) | ||||
537970.HCAN_0590 | PF00828 | ||||
537970.HCAN_0828 | (PF01509) | ||||
537970.HCMG_00109 | (PF01715) | ||||
537970.HCMG_01474 | (PF01746) | ||||
537970.HCMG_01475 | (PF01245) | ||||
537970.HCMG_01473 | (PF01782) | ||||
537970.HCMG_00875 | (PF00162) | ||||
537970.HCAN_1382 | (PF01795) | ||||
537970.HCAN_1387 | (PF10431) | ||||
537970.HCAN_0163 | (PF01041) |
Detailed merged results for each protein sequence
- Detailed merged results as table (merge_results.html)
- Detailed merged results as tab delimited file (merge_results.csv)
Individual results for each protein sequence
- EffectiveELD predictions (PROTEINS.ELD.TXT)
- Predotar predictions using animal/human model (Predotar_output_modelANIMAL.TXT)
- Predotar predictions using plant model (Predotar_output_modelPLANT.TXT)
Genome based results
Summary
- Gram negative: YES (FDR = 0.5 %)
- Functional Type III secretion system: NO (FDR = 12.5 %)
- Functional Type IV secretion system: NO (FDR = 7.2 %)
- Functional Type VI secretion system: YES (FDR = 7.7 %)
Estimated copy number = 1.25 (10/8 KEGG proteins)
Individual results for each secretion system
- List of 100 most important COGs/NOGs for prediction of functional Type III secretion system (T3_top100_COGS.xls)
- List of 100 most important COGs/NOGs for prediction of functional Type IV secretion system (T4_top100_COGS.xls)
- List of 100 most important COGs/NOGs for prediction of functional Type VI secretion system (T6_top100_COGS.xls)
- List of COGs assigned to Type III secretion system in KEGG (T3SS_KEGG_cmp.xls)
- List of COGs assigned to Type IV secretion system in KEGG (T4SS_KEGG_cmp.xls)
- List of COGs assigned to Type VI secretion system in KEGG (T6SS_KEGG_cmp.xls)
Parameters:
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EFFECTIVE_T3_OLD=selective
EFFECTIVE_T3_NEW=selective
PREDOTAR_ANIMAL_OR_PLANT=a
PROTEINS=INPUT PROTEINS
MODUS=genome
RUN_PREDOTAR=T
RUN_EFFECTIVE_T3=T
RUN_T4SEpre=0.5
RUN_EFFECTIVE_CCBD=T
RUN_EFFECTIVE_ELD=4
CheckM_COMPLETENESS=
RUN_EffectiveS346=T
GENOTYPE=COG Profile
EMAIL=
==========================================================
Estimated copy number = 1.25 (10/8 KEGG proteins)